PXBマウス関連
Evaluation of human hepatocyte chimeric mice as a model for toxicological investigation using panomic approaches--effect of acetaminophen on the expression profiles of proteins and endogenous metabolites in liver, plasma and urine
PXBマウス関連
Yamamoto T, Tomizawa K, Fujikawa M, Sato Y, Yamada H, Horii I.
J Toxicol Sci. 2007 Aug;32(3):205-15.
Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C Virus and its susceptibility to interferon
PXBマウス関連
Hiraga N, Imamura M, Tsuge M, Noguchi C, Takahashi S, Iwao E, Fujimoto Y, Abe H, Maekawa T, Ochi H, Tateno C, Yoshizato K, Sakai A, Sakai Y, Honda M, Kaneko S, Wakita T, Chayama K.
FEBS Lett. 2007 May 15;581(10):1983-7. Epub 2007 Apr 20.
Evaluation of Cyclophilin Inhibitor in Hepatitis C Virus-Infected Chimeric Mice In Vivo
PXBマウス関連
Inoue K, Umehara T, Ruegg UT, Yasui F, Watanabe T, Yasuda H, Dumont JM, Scalfaro P, Yoshiba M, Kohara M.
Hepatology. 2007 Apr;45(4):921-8.
Early Dynamics of Hepatitis B Virus in Chimeric Mice Carrying Human Hepatocytes Monoinfected or Coinfected with Genotype G
PXBマウス関連
Sugiyama M, Tanaka Y, Sakamoto T, Maruyama I, Shimada T, Takahashi S, Shirai T, Kato H, Nagao M, Miyakawa Y, Mizokami M.
Hepatology. 2007 Apr;45(4):929-37.
Application of chimeric mice with humanized liver for predictive adme
PXBマウス関連
Katoh M, Yokoi T.
Drug Metab Rev. 2007;39(1):145-57.
Humanization of Excretory Pathway in Chimeric Mice with Humanized Liver
PXBマウス関連
Okumura H, Katoh M, Sawada T, Nakajima M, Soeno Y, Yabuuchi H, Ikeda T, Tateno C, Yoshizato K, Yokoi T.
Toxicol Sci. 2007 Jun;97(2):533-8. Epub 2007 Mar 6.
In Vivo Drug Metabolism Model for Human Cytochrome P450 Enzyme Using Chimeric Mice with Humanized Liver
PXBマウス関連
Katoh M, Sawada T, Soeno Y, Nakajima M, Tateno C, Yoshizato K, Yokoi T.
J Pharm Sci. 2007 Feb;96(2):428-37.
Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice
PXBマウス関連
Nakagawa S, Umehara T, Matsuda C, Kuge S, Sudoh M, Kohara M.
Biochem Biophys Res Commun. 2007 Feb 23;353(4):882-8. Epub 2006 Dec 22.
Humanized mice in translational biomedical research.
PXBマウス関連
Shultz LD, Ishikawa F, Greiner DL.
Nat Rev Immunol. 2007 Feb;7(2):118-30.
Evaluation of Human CYP1A2 and CYP3A4 mRNA Expression in Hepatocytes from Chimeric Mice with Humanized Liver
PXBマウス関連
Yoshitsugu H, Nishimura M, Tateno C, Kataoka M, Takahashi E, Soeno Y, Yoshizato K, Yokoi T, Naito S.
Drug Metab Pharmacokinet. 2006 Dec;21(6):465-74.
Emergence of a Novel Lamivudine-Resistant Hepatitis B Virus Variant with a Substitution Outside the YMDD Motif
PXBマウス関連
Yatsuji H, Noguchi C, Hiraga N, Mori N, Tsuge M, Imamura M, Takahashi S, Iwao E, Fujimoto Y, Ochi H, Abe H, Maekawa T, Tateno C, Yoshizato K, Suzuki F, Kumada H, Chayama K.
Antimicrob Agents Chemother. 2006 Nov;50(11):3867-74. Epub 2006 Sep 18.
Influence of Hepatitis B Virus Genotypes on the Intra- and Extracellular Expression of Viral DNA and Antigens
PXBマウス関連
Sugiyama M, Tanaka Y, Kato T, Orito E, Ito K, Acharya SK, Gish RG, Kramvis A, Shimada T, Izumi N, Kaito M, Miyakawa Y, Mizokami M.
Hepatology. 2006 Oct;44(4):915-24.
Characterization of Humanized Liver from Chimeric Mice Using Coumarin as a Human CYP2A6 and Mouse CYP2A5 Probe
PXBマウス関連
Aoki K, Kashiwagura Y, Horie T, Sato H, Tateno C, Ozawa N, Yoshizato K.
Drug Metab Pharmacokinet. 2006 Aug;21(4):277-85.
Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model
PXBマウス関連
Umehara T, Sudoh M, Yasui F, Matsuda C, Hayashi Y, Chayama K, Kohara M.
Biochem Biophys Res Commun. 2006 Jul 21;346(1):67-73. Epub 2006 May 24.
Infection of Human Hepatocyte Chimeric Mouse With Genetically Engineered Hepatitis B Virus
PXBマウス関連
Tsuge M, Hiraga N, Takaishi H, Noguchi C, Oga H, Imamura M, Takahashi S, Iwao E, Fujimoto Y, Ochi H, Chayama K, Tateno C, Yoshizato K.
Hepatology. 2005 Nov;42(5):1046-54.
Efficient In Vivo Xenogeneic Retroviral Vector-Mediated Gene Transduction into Human Hepatocytes
PXBマウス関連
Emoto K, Tateno C, Hino H, Amano H, Imaoka Y, Asahina K, Asahara T, Yoshizato K.
Hum Gene Ther. 2005 Oct;16(10):1168-74.
Evaluation of mRNA expression of human drug-metabolizing enzymes and transporters in chimeric mouse with humanized liver
PXBマウス関連
Nishimura M, Yoshitsugu H, Yokoi T, Tateno C, Kataoka M, Horie T, Yoshizato K, Naito S.
Xenobiotica. 2005 Sep;35(9):877-90.
In vivo induction of human cytochrome P450 3A4 by rifabutin in chimeric mice with humanized liver
PXBマウス関連
Katoh M, Watanabe M, Tabata T, Sato Y, Nakajima M, Nishimura M, Naito S, Tateno C, Iwasaki K, Yoshizato K, Yokoi T.
Xenobiotica. 2005 Sep;35(9):863-75.
Expression of Human Phase Ⅱ Enzymes in Chimeric Mice with Humanized Liver
PXBマウス関連
Katoh M, Matsui T, Okumura H, Nakajima M, Nishimura M, Naito S, Tateno C, Yoshizato K, Yokoi T.
Drug Metab Dispos. 2005 Sep;33(9):1333-40. Epub 2005 Jun 2.
In Vivo Induction of Human Cytochrome P450 Enzymes Expressed in Chimeric Mice with Humanized Liver
PXBマウス関連
Katoh M, Matsui T, Nakajima M, Tateno C, Soeno Y, Horie T, Iwasaki K, Yoshizato K, Yokoi T.
Drug Metab Dispos. 2005 Jun;33(6):754-63. Epub 2005 Mar 15.
