Tg & KO Animal Services
High quality and high standard technical services related to transgenic and knock out animal production with fast and reliable delivery.
Service Range and Steps for BAC transgenics (mice, rats, rabbits)
The BAC transgenic vectors, containing endogenous protein regulatory sequences have been introduced into the pronuclear ova. By using a BAC gene construct, we can expect to have the same expression profiles as the endogenus gene and as a result can measure the relative rates of transcription for each gene (We call this the "Semi-knock-in" strategy)
Pronuclear Microinjection (mice, rats, rabbits)
We create transgenic mice/rats/rabbits by pronuclear injection with transgenic expression cassettes prepared by the customer.
Knock-out & Knock-in mice
We create genetically engineered ("knock-out" or "knock-in") mice via homologous recombination in the embryonic stem (ES) cells.
Breeding and Other Services
To create genetically engineered animals in practice is complicated. It requires the the technologies of molecular and developmental biology and embryology and animal breeding skills.
